The Blog

The PPC team at American Society For Mass Spectrometry (ASMS) 2023, look at those happy faces! Jérôme Vialaret: Determination of a biomarkers panel to predict the response to treatment with dexamethasone for Sars-Cov2 / COVID-19 pneumonia Florine Leipp: Development of...

Last week, more than forty members of the Fondation pour la Recherche Médicale came to visit the laboratories of the Institute For Neurosciences Of Montpellier and the Institute for Regenerative Medicine & Biotherapy. Welcomed by Dr Sylvain Lehmann and his teams,...

Since Tuesday, Marie-Laure PONS can call herself a doctor after defending her PhD subject, development of an LC-MRM method for the quantification of synucleins in human builogical fluids in the context of neurodegenerative diseases. Many congratulations for the...

Many congratulations to doctor Amandine Amalric. Yesterday she defended her PhD subject, development of new cancer biomarkers based on RNA epigenetics, with great professionalism and confidence. We are all very proud of the work you have accomplished over the past...

The PPC team is very proud to announce that Jerome Vialaret has brilliantly defended his accreditation to supervise research (HDR) entitled: Biochemical diagnosis of neurodegenerative diseases: past, present and future. The HDR “recognises the candidate's high level...

Brain tumour: scientists from Montpellier develop a revolutionary diagnostic test Éric Rivals, a researcher at the LIRMM (Montpellier Laboratory of Informatics, Robotics and Microelectronics), Alexandre David, a biologist at the Institute of Functional Genomics, and...

Last week, two of our colleagues (Aurore Attina and Jana Kindermans Collinet) attended the Analytics2022 conference in Nantes, France. They met with our colleagues from the Montpellier proteome pole (PPM). Many thanks to the organizers for a wonderful and interesting...

This month, two students (Léa Barre and Maribelle Dossou-Yovo) from the Master 1 Biology-Health program followed us around the laboratory. We showed them how to work safely in a research lab and what it is like to do experiments. We hope they will be able to put this...

Happy to share our last paper in Analytical Chemistry on epitranscriptomics. We combine RNA mass spectrometry with machine learning to discriminate and predict glioma grades with unmet accuracy. This project was generously supported by Région Occitanie and SIRIC...

Last Friday, our intern Margaux Vignon presented a poster of a clinical study carried out within the Montpellier University Hospital at the European Congress of Periodontics and Implantology EuroPerio10 in Copenhagen. Poster title: Evaluation of post-operative...

We are happy to see our Technical Head, Jerome Vialaret, at the XIV Annual Congress of the European Proteomic Association in Leipzig. #EuPA2022

We continue our yearly tradition of bringing a Belgian student into our team. This year we are pleased to welcome Nikita De Wilde from HOWEST University of Applied Sciences (Hogeschool West-Vlaanderen), who will be doing a 4-month internship for the end of her Licence...

Let us introduce Margaux Vignon, another M2 BIOTIN student who will carry out her internship of six months in our laboratory. In a first phase, she will perform MSD immunoassays with Nelly Ginestet for the determination of protein biomarkers in patients with COVID 19....

Out now in Journal of Neural Transmission! This paper shows how blood amyloid and tau biomarkers can be used as predictors of cerebrospinal fluid profiles related to Alzhiemer's disease. This could be an important change in the need for lumbar puncture and perhaps the...

This week we are happy to welcome another intern, Roumeissa Zouiher, a M2 BIOTIN student. She will stay six months to help our engineer Aurore Attina established a quality control for the analysis of RNA modifications by mass spectrometry. To do so, she will work in...

It's almost February, which means our interns are starting to arrive! This week we welcome our first intern of the year to arrive, Morgan Dornadic! She will be working by the side of our PhD student Marie-Laure Pons and will help her to develop a RT-QuIC (Real time...

Biomarkers for Alzheimer's disease, which can be measured by a simple blood test, will revolutionise the way Alzheimer's disease is diagnosed, making it simpler, quicker and less invasive. Today, lumbar puncture is often required to analyse cerebrospinal fluid.The...

The past two years have been a fruitful collaboration between our laboratory and the European Innovation Center from Shimadzu.A joint study for early detection of Alzheimer's disease biomarkers using mass spectrometry opens the door to new research advances. We...

This week, the M2 - DMCC students had the opportunity to visit our platform within the IRMB, accompanied by Professor Hirtz. We are always happy to show our platform to people interested in research!

Meet our team: a combination of engineers, technicians and PhD students. All our individual skills and knowledge combined makes our platform so much more interesting!

We are pleased to share with you the latest poster from our PhD student Marie-Laure PONS on the analysis of the synucleins by LC-MRM in biological fluids (plasma, CSF and saliva) in the context of neurodegenerative diseases such as Parkinson's disease.

Latest news! Our new Simoa HD-X from Quanterix has arrived to replace our previous model HD-1. This model is a fully automated Simoa bead-based immunoassay platform and delivers major productivity improvements, greater user flexibility, unparalleled sensitivity, and...

Thanks to LCGC to share the work done by our team on quantification of tau and ptau by LC-MS/MS for Alzheimer's disease ! Jerome VIALARET, Christophe HIRTZ, Sylvain LEHMANN, Laura FICHTER More information :...

Shimadzu: "Even during that pandemic situation, we continue to develop application, instrument solution for solving analytical problems with our partners accross Europe!" Our PlasmaBoost project (beta amyloid in blood) and the thesis of Marie-Laure PONS (synuclein...

Celebrate women's achievement. Raise awareness against bias. Take action for equality. #ChooseToChallenge With a special shoutout to the women in our team : Aurore ATTINA, Laura FICHTER, Nelly GINESTET, Jana KINDERMANS, Lisa MORICHON et Marie-Laure PONS. #IWD2021...

We are happy to announce a new project financed by the INCa in the framework of the Montpellier-based partnership* SMART: RNA methylation and FTO activity steer colorectal cancer cell phenotype Fat mass and Obesity-associated protein (FTO), a nuclear m6A demethylase,...

The PPC is happy to announce that we are strengthening our team with two new flemish students: Guillaume Le Berre and Ryan Trouvé. Both are students at HOWEST University of Applied Sciences (Hogeschool West-Vlaanderen) and are doing an internship during 4 months, at...

Axelle Vinot is doing an 8-week internship with us as part of her BTS with option in biotechnology. She will carry out assays on the Tau protein, an essential biomarker in the diagnosis of Alzheimer's disease, particularly in mass spectrometry.

Étienne Mondesert is a medical biology intern at the Montpellier University Hospital, doing a Master 2 internship at our platform. His work focuses on mass spectrometry quantification and clinical evaluation of a biomarker in the context of Parkinson disease.

For the Alzheimer’s Association International Conference (AAIC), our assistant engineer Jana Kindermans made a scientific poster on the early detection of Alzheimer’s disease biomarker, namely plasma amyloid peptides. For the quantification of these plasma amyloid...

Recently, our PhD student Marie-Laure PONS gave a presentation for her the thesis follow up committee. After one year of doing research and experimenting, her topic is beginning to take shape: the development of an innovative multiplex and targeted mass spectrometry...

Very proud of the financial support of @IsiteMUSE for our new CoVIMOD project dealing with an exhaustive analysis of the modification landscape of viral and cellular RNAs in SARS-CoV2 infection and the study of their functional impact on virus replication and cell...

Interested in using our numerous skills and techniques to analyse your samples? This workflow explains exactly how we work. For more information, check our website ppc-montpellier.com or contact us directly! #massspectrometry #proteomic #epitranscriptomics

We would like to introduce Pablo Mohaupt, a new PhD student who joins our team. As part of MIRIADE.eu, Pablo will work on novel ideas and methods contributing to biomarker discovery in neurodegenerative diseases. His main focus is on mass spectrometric analytical...

Thanks to the latest ELLA system, we are joining the fight against the COVID-19 virus for the Immuno-monitoring of patients. In partnership with the virology department, the PPC participates in the evaluation of the worsening clinical condition of patients in order to...

This Friday, February 28th, Professor Sylvain Lehmann and our PhD student Marie-Laure Pons were present at the teachers’ symposium "From Research to Clinic, Encounter on Neuroscience" at the New Faculty of Medicine of Montpellier. They had the opportunity to present...

Last week we were happy to welcome two new interns Salomé and Michelle, who will be part of our team for the upcoming time. Salomé Coppens is a M2 BIOTIN student. She will stay six months to work the development of a method of detection and localization of RNA...

Dr. Syrine Dimassi, graduated with a PhD in materials chemistry and more specifically in the field of biopolymers and medical devices, joined our team a few months ago as a Temporary Teaching and Research Associate. She will develop a multiplex and targeted mass...

Are you interested measuring the amount of monoclonal antibodies in human serum? We offer you nSmol: a sample preparation allowing to decrease the sample complexity before LC/MS quantitation of monoclonal antibodies. This method used a limited sample volume (5µL) and...

Congratulations to our technical manager Jérôme Vialaret for his PhD in science entitled "Development and validation of innovative proteomic methods for clinical biochemistry applications"!

During the IRMB open doors on November 20, we had the opportunity to hear from Mrs Emilie BARDE (Director of Research and Innovation at the CHU de Montpellier), Mr Jacques MERCIER (Vise-President of Research at the Université de Montpellier) and Mr Jacques CAVAILLE...

Our first year doctoral student Marie-Laure Pons, in collaboration with Shimadzu Corporation, had the opportunity to present her thesis research project "mass spectrometry detection of synucleins and its isoformes in blood and CSF of patients with neurodegenerative...

This Wednesday May 22nd, Jérôme Vialaret, our mass spectrometry engineer, was present to explain the automation of biological sample preparation with AssayMap Bravo at the ELRIGfr Congress (OMICS, DIAGNOSTIC & LAB AUTOMATION) in Montpellier. We would like to thank...

Marie-Laure Pons has join our team in order to perform a CIFRE PhD in collaboration with the SHIMADZU company. Her project is on the devolpment of innovative approaches by mass spectrometry to detect and quantify biomarkers of interest in neurodegenerative diseases...

Some of you may have recognized the SHIMADZU CORPORATION scotch! Thanks a lot to those who helped us opening this big box. We are proud to present our new Maldi-Tof: the AXIMA Assurance! Stay tuned, you will soon read more about the project for this mass spectrometer.