Mass Spectrometry
MRM or High Resolution, we have the solution to your problemTo carry out its research and service activities, the PPC is equipped with the latest generation LC-MS/MS mass spectrometry systems (Agilent Technologies, Bruker Daltonics and Shimadzu) as well as two biological sample preparation robots which represent an investment of 2.5 million Euros thanks to funds from the Occitania Region, mainly UM and CHU.
Multiple Reaction Monitoring
Multiple Reaction Monitoring (MRM) is a MS technique widely used in the clinical setting for the targeted quantification of analytes or small molecules.
LCMS 8060NX Shimadzu
The development of MRM methods can be carried out on different types of matrices, ranging from biological fluids (whole blood, urine) to cell culture, for example.
High Resolution Mass Spectrometry
High-resolution mass spectrometry allows the identification and characterization of a large number of proteins in complex mixtures.
Impact II Bruker + nanoElute Bruker
High performance proteomics and metabolomics studies using the impact II QTOF provide insight into how rational strain design increased bio-production efficiency. The Bruker impact II QTOF system is well suited to bottom-up proteomic and metabolomic workflows, and can be used to map the results of both metabolic and proteomic changes onto biochemical pathways.
Bruker nanoElute is designed with years of proteomics know-how and nano-UHPLC expertise to deliver robust and reliable operation from the moment of installation through years of OMICS knowledge generation.
TimsTOF HT Bruker + Evosep One Evosep
The new timsTOF HT mass spectrometer is equipped with the 4th generation high capacity TIMS-XR analyzer and advanced digitizer technology (ADT). It offers higher dynamic range for unmatched analytical depth and quantitation in high-throughput proteomics experiments. The timsTOF HT is fully CCS-enabled and supports all PASEF acquisition modes including PASEF, dia-PASEF and prm-PASEF achieving flexibility in 4D-Proteomics™. Simply uncompromised proteomic depth at scale.
The Evosep One is a standardized platform designed for robustness and high throughput. This is achieved by using Evotips as disposable trap columns, where samples are loaded and desalted offline. The autosampler picks up the tip and integrates elution with liquid chromatography. This removes sample handling steps and reduces injection cycle overheads.
6546 LC/Q-TOF Agilent
The 6546 high resolution mass spectrometer accelerates your lab’s capabilities by enabling comprehensive workflows in metabolomics research. With simultaneous high sensitivity, wide dynamic range, high resolution, isotope fidelity, and accurate mass measurements, the resulting high data quality provides the level of confidence you need for fast and simplified data review processes.
High Performance Mass Detection
By a Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometer.
Axima Assurance Shimadzu
- Linear MALDI-TOF mass spectrometer for intact mass information and reliable protein profiles
- The affordable, robust solution for all laboratories which require a manual or automated routine system for a wide variety of samples.
- High-sensitivity system with variable nitrogen laser up to 50 Hz, and a variety of target plates to meet all sample throughput requirements.
Ideal for high throughput QA/QC analyses (Oligonucleotides / primers, synthetic peptides / proteins, polymers, small molecules, etc…)
Clinical Proteomics Platform
Institute for Regenerative Medicine & Biotherapy (IRMB)
Hôpital Saint Eloi
80 rue Augustin Fliche
34295 MONTPELLIER – Cedex 5
FRANCE