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2021

 

 

 

 

 

 

 

2020

Lehmann S, Dumurgier J, Ayrignac X, Marelli C, Alcolea D, Ormaechea JF, Thouvenot E, Delaby C, Hirtz C, Vialaret J, Ginestet N, Bouaziz-Amar E, Laplanche JL, Labauge P, Paquet C, Lleo A, Gabelle A.
Alzheimer’s Disease Neuroimaging Initiative (ADNI).
Cerebrospinal fluid A beta 1-40 peptides increase in Alzheimer’s disease and are highly correlated with phospho-tau in control individuals.
Alzheimers Res Ther. 2020 Oct 2;12(1):123. PMID: 33008460; PMCID: PMC7532565. doi: 10.1186/s13195-020-00696-1
https://www.ncbi.nlm.nih.gov/pubmed/33008460 

Chenini S, Delaby C, Rassu AL, Barateau L, Vialaret J, Hirtz C, Dupuy AM, Lehmann S, Jaussent I, Dauvilliers Y.
Hepcidin and ferritin levels in restless legs syndrome: a case-control study.
Sci Rep. 2020 Jul 17;10(1):11914. PMID: 32681031; PMCID: PMC7367854. doi: 10.1038/s41598-020-68851-0
https://www.ncbi.nlm.nih.gov/pubmed/32681031

Ayrignac X, Le Bars E, Duflos C, Hirtz C, Maleska Maceski A, Carra-Dallière C, Charif M, Pinna F, Prin P, Menjot de Champfleur N, Deverdun J, Kober T, Marechal B, Fartaria MJ, Corredor Jerez R, Labauge P, Lehmann S.
Serum GFAP in multiple sclerosis: correlation with disease type and MRI markers of disease severity.
Sci Rep. 2020 Jul 2;10(1):10923. PMID: 32616916; PMCID: PMC7331703. doi: 10.1038/s41598-020-67934-2
https://www.ncbi.nlm.nih.gov/pubmed/32616916

Bailey DM, Lanéelle D, Trihan JE, Marchi N, Stacey BS, Tamiya K, Washio T, Tuaillon E, Hirtz C, Lehmann S, Ogoh S, Normand H.
Gravitational Transitions Increase Posterior Cerebral Perfusion and Systemic Oxidative-nitrosative Stress: Implications for Neurovascular Unit Integrity.
Neuroscience. 2020 Aug 10;441:142-160. Epub 2020 Jun 2. PMID: 32502571. doi: 10.1016/j.neuroscience.2020.05.048
https://www.ncbi.nlm.nih.gov/pubmed/32502571

Rossi E, Tran NT, Hirtz C, Lehmann S, Taverna M.
Efficient extraction of intact HSA-Aβ peptide complexes from sera: Toward albuminome biomarker identification.
Talanta. 2020 Aug 15;216:121002. Epub 2020 Apr 9. PMID: 32456932. doi: 10.1016/j.talanta.2020.121002
https://www.ncbi.nlm.nih.gov/pubmed/32456932

Barthélemy NR, Bateman RJ, Hirtz C, Marin P, Becher F, Sato C, Gabelle A, Lehmann S.
Cerebrospinal fluid phospho-tau T217 outperforms T181 as a biomarker for the differential diagnosis of Alzheimer’s disease and PET amyloid-positive patient identification.
Alzheimers Res Ther. 2020 Mar 17;12(1):26. PMID: 32183883; PMCID: PMC7079453. doi: 10.1186/s13195-020-00596-4
https://www.ncbi.nlm.nih.gov/pubmed/32183883

Marelli C, Hourregue C, Gutierrez LA, Paquet C, Menjot de Champfleur N, De Verbizier D, Jacob M, Dubois J, Maleska AM, Hirtz C, Navucet S, Bennys K, Dumurgier J, Cognat E, Berr C, Magnin E, Lehmann S, Gabelle A.
Cerebrospinal Fluid and Plasma Biomarkers do not Differ in the Presenile and Late-Onset Behavioral Variants of Frontotemporal Dementia.
J Alzheimers Dis. 2020;74(3):903-911. PMID: 32083577. doi: 10.3233/JAD-190378
https://www.ncbi.nlm.nih.gov/pubmed/32083577 

Ployon S, Attina A, Vialaret J, Walker AS, Hirtz C, Saucier C.
Laccases 2 & 3 as biomarkers of Botrytis cinerea infection in sweet white wines.
Food Chem. 2020 Jun 15;315:126233. Epub 2020 Jan 20. PMID: 32018078. doi: 10.1016/j.foodchem.2020.126233
https://www.ncbi.nlm.nih.gov/pubmed/32018078 

2019

Vialaret J, Lehmann S, Hirtz C.
Intact Protein Analysis by LC-MS for Characterizing Biomarkers in Cerebrospinal Fluid.
Methods Mol Biol. 2019;1959:163-172. doi: 10.1007/978-1-4939-9164-8_11
https://www.ncbi.nlm.nih.gov/pubmed/30852822

Lepleux C, Marie-Brasset A, Temelie M, Boulanger M, Brotin E,  Goldring MB, Hirtz C, Varès G, Nakajima T, Saintigny Y, Savu D, Chevalier F.
Bystander effectors of chondrosarcoma cells irradiated at different LET impair proliferation of chondrocytes.
Journal of Cell Communication and Signaling. doi: 10.1007/s12079-019-00515-9
https://www.ncbi.nlm.nih.gov/pubmed/30903603

Relaño-Ginés A, Lehmann S, Deville de Périère D, Hirtz C.
Dental stem cells as a promising source for cell therapies in neurological diseases.
Crit Rev Clin Lab Sci. 2019 May;56(3):170-181. doi: 10.1080/10408363.2019.1571478
https://www.ncbi.nlm.nih.gov/pubmed/30931658

Peyron PA, Lehmann S, Delaby C, Baccino E, Hirtz C.
Biochemical markers of time since death in cerebrospinal fluid: a first step towards “Forensomics”.
Crit Rev Clin Lab Sci. (2019) In press (IF 6.481). doi: 10.1080/10408363.2019.1619158
https://www.ncbi.nlm.nih.gov/pubmed/31088325

Paterson RW, Gabelle A, Lucey BP, Barthélemy NR, Leckey CA, Hirtz C, Lehmann S, Sato C, Patterson BW, West T, Yarasheski K, Rohrer JD, Wildburger NC, Schott JM, Karch CM, Wray S, Miller TM, Elbert DL, Zetterberg H, Fox NC, Bateman RJ.
SILK studies – capturing the turnover of proteins linked to neurodegenerative diseases.
Nat Rev Neurol. 2019 Jul;15(7):419-427. doi: 10.1038/s41582-019-0222-0
https://www.ncbi.nlm.nih.gov/pubmed/31222062

Murall CL, Rahmoun M, Selinger C, Baldellou M, Bernat C, Bonneau M, Boué V, Buisson M, Christophe G, D’Auria G, Taroni F, Foulongne V, Froissart R, Graf C, Grasset S, Groc S, Hirtz C, Jaussent A, Lajoie J, Lorcy F, Picot E, Picot MC, Ravel J, Reynes J, Rousset T, Seddiki A, Teirlinck M, Tribout V, Tuaillon É, Waterboer T, Jacobs N, Bravo IG, Segondy M, Boulle N, Alizon S.
Natural history, dynamics, and ecology of human papillomaviruses in genital infections of young women: protocol of the PAPCLEAR cohort study.
BMJ Open. 2019 Jun 11;9(6):e025129. doi: 10.1136/bmjopen-2018-025129 
https://www.ncbi.nlm.nih.gov/pubmed/31189673

Pontier D, Picart C, El Baidouri M, Roudier F, Xu T, Lahmy S, Llauro C, Azevedo J, Laudié M, Attina A, Hirtz C, Carpentier MC, Shen L, Lagrange T.
The m6A pathway protects the transcriptome integrity by restricting RNA chimera formation in plants.
Life Sci Alliance. 2019 May 29;2(3). doi: 10.26508/lsa.201900393
https://www.ncbi.nlm.nih.gov/pubmed/31142640

Contreras-Aguilar MD, Vialaret J, de Périère DD, Escribano D, Lehmann S, Tecles F, Cerón JJ, Hirtz C.
Variation of human salivary alpha-amylase proteoforms in three stimulation models.
Clin Oral Investig. 2019 Aug 6. doi: 10.1007/s00784-019-03021-9 
https://www.ncbi.nlm.nih.gov/pubmed/31388762

Thouvenot E, Demattei C, Lehmann S, Maceski-Maleska A, Hirtz C, Juntas-Morales R, Pageot N, Esselin F, Alphandéry S, Vincent T, Camu W.
Serum neurofilament light chain at time of diagnosis is an independent prognostic factor of survival in amyotrophic lateral sclerosis.
Eur J Neurol. 2019 Aug 22. doi: 10.1111/ene.14063
https://www.ncbi.nlm.nih.gov/pubmed/31437330

2018
Vialaret J, Wessels H, van Gool AJ, Lehmann S, Gabelle A, Wood J, Bern M, Paape R, Suckau D, Kruppa G and C Hirtz.
Towards a routine application of Top-Down approaches for Label-Free discovery Workflows.
Journal of Proteomics (IF :3.88). 2018 Mar 20;175:12-26. doi: 10.1016/j.jprot.2017.08.003 
https://www.ncbi.nlm.nih.gov/pubmed/28855124
Mertens B, Orti V, Vialaret J, Gibert P, Relaño-Ginés A, Lehmann S, de Périère DD, Hirtz C.
Assessing a multiplex-targeted proteomics approach for the clinical diagnosis of periodontitis using saliva samples.
Bioanalysis. 2018 Jan;10(1):35-45 (IF:2.7). doi: 10.4155/bio-2017-0218
https://www.ncbi.nlm.nih.gov/pubmed/29243487
Dauvilliers Y, Chenini S, Vialaret J, Delaby C, Guiraud L, Gabelle A, Lopez R, Hirtz C, Jaussent I, Lehmann S.
Association between serum hepcidin level and restless legs syndrome.
Mov Disord. 2018 Feb 8. doi: 10.1002/mds.27287 
https://www.ncbi.nlm.nih.gov/pubmed/29418021

Vialaret J, Picas A, Delaby C, Bros P, Lehmann S, Hirtz C.
Nano-flow vs standard-flow: Which is the more suitable LC/MS method for quantifying hepcidin-25 in human serum in routine clinical settings?
Journal of Chromatography B. 2018, Vol 1086: 110-117. doi: 10.1016/j.jchromb.2018.04.003
https://www.ncbi.nlm.nih.gov/pubmed/29660664

Orti V, Mertens B, Vialaret J, Gibert P, Relaño-Ginés A, Lehmann S, de Périère DD, Hirtz C.
Data from a targeted proteomics approach to discover biomarkers in saliva for the clinical diagnosis of periodontitis.
Data in Brief. 2018, Vol 18, Pages 294-299. doi: 10.1016/j.dib.2018.03.036 
https://www.ncbi.nlm.nih.gov/pubmed/29900194
Vialaret J, Wessels H, van Gool AJ, Lehmann S, Gabelle A, Wood J, Bern M, Paape R, Suckau D, Kruppa G and Hirtz C.
Identification of multiple proteoforms biomarkers on clinical samples by routine Top-Down approaches.
Data in Brief. 2018, Vol 18, June 2018, Pages 1013-1021. doi: 10.1016/j.dib.2018.03.114 
https://www.ncbi.nlm.nih.gov/pubmed/29900270
Vialaret J, Kadi S, Tiers L,  O’Flynn R, Lehmann S and Hirtz C.
Albumin depletion of human serum to improve quantitative clinical proteomics.
Current Topics in Peptide & Protein Research, 2018 Sous presse. 
https://www.researchgate.net/publication/331015018
Fortea J, Carmona-Iragui M, Benejam B, Fernández S, Videla L, Barroeta I, Alcolea D, Pegueroles J, Muñoz L, Belbin O, de Leon MJ, Maceski AM, Hirtz C, Clarimón J, Videla S, Delaby C, Lehmann S, Blesa R, Lleó A.
Plasma and CSF biomarkers for the diagnosis of Alzheimer’s disease in adults with Down syndrome: a cross-sectional study.
Lancet Neurol. 2018 : 17(10):860-869. doi: 10.1016/S1474-4422(18)30285-0
https://www.ncbi.nlm.nih.gov/pubmed/30172624
Piton M, Hirtz C, Desmetz C, Milhau J, Lajoix AD, Bennys K, Lehmann S, Gabelle A.
Alzheimer’s Disease: Advances in Drug Development.
J Alzheimers Dis. 2018;65(1):3-13. doi: 10.3233/JAD-180145
https://www.ncbi.nlm.nih.gov/pubmed/30040716
Vialaret J, Broutin S, Pugnier C, Santelé S, Jaffuel A, Barnes A, Tiers L, Pelletier L, Lehmann S, Paci A, Hirtz C.
What sample preparation should be chosen for targeted MS monoclonal antibody quantification in human serum?
Bioanalysis. 2018 May 1;10(10):723-735. doi: 10.4155/bio-2018-0027
https://www.ncbi.nlm.nih.gov/pubmed/29771137
Incamps A, Saez-Boiteau C, Tiede SL, Rebillard P, Schulte J, Vialaret J, Beinrucker A, Lehmann S, Hirtz C.
Impact of biological matrix on inflammatory protein biomarker quantification based on targeted mass spectrometry.
Bioanalysis. 2018 Sep 1;10(17):1383-1399. doi: 10.4155/bio-2018-0149
https://www.ncbi.nlm.nih.gov/pubmed/30207162
Darlix A, Hirtz C, Thezenas S, Maceski A, Gabelle A, Lopez-Crapez E, De Forges H, Firmin N, Guiu S, Jacot W, Lehmann S.
The prognostic value of the Tau protein serum level in metastatic breast cancer patients and its correlation with brain metastases.
BMC Cancer. 2019 Jan 30;19(1):110. doi: 10.1186/s12885-019-5287-z
https://pubmed.ncbi.nlm.nih.gov/30700265/ 
Molinari N, Roche S, Peoc’h K, Tiers L, Séveno M, Hirtz C, Lehmann S.
Sample Pooling and Inflammation Linked to the False Selection of Biomarkers for Neurodegenerative Diseases in Top-Down Proteomics: A Pilot Study.
Front Mol Neurosci. 2018 Dec 18;11:477. doi: 10.3389/fnmol.2018.00477
https://www.ncbi.nlm.nih.gov/pubmed/30618622

 

2017
Maleska A, Hirtz C, Casteleyn E, Villard O, Ducos J, Avignon A, Sultan A, Lehmann S.
Comparison of HbA1c detection in whole blood and dried blood spots using an automated ion-exchange HPLC system.
Bioanalysis. 2017 Mar;9(5):427-434 (IF:2.7). doi: 10.4155/bio-2016-0278
https://www.ncbi.nlm.nih.gov/pubmed/28220711
Lasocki S, Puy H, Mercier G, Lehmann S, Asfar P, Mercat A, Gaillard T, Gergaud S, Lasocki S, Sargentini C, Geneve C, Montravers P, Lefebvre T, Puy H, Mercier G, Nagot N, Delaby C, Hirtz C, Lehmann S, Vialaret J, Chanques G, Jaber S, Asehnoune K, Roquilly A, Dahyot-Fizelier C, Mimoz O, Isslame S, Seguin P, Barbaz M, Ferrandiere M.
Impact of iron deficiency diagnosis using hepcidin mass spectrometry dosage methods on hospital stay and costs after a prolonged ICU stay: Study protocol for a multicentre, randomised, single-blinded medico-economic trial.
Anaesth Crit Care Pain Med. 2017 Sep 14. pii: S2352-5568(17)30089-9 (IF:1.54). doi: 10.1016
https://www.ncbi.nlm.nih.gov/pubmed/28919067
Quijada‐Morin N, Garcia F, Lambert K, Walker A‐S, Tiers L, Viaud M, Sauvage F‐X, Hirtz C and Saucier C.
Strain effect on extracellular laccase activities from Botrytis cinereal.
Australian Journal of Grape and Wine Research. (2017) (IF:2.635). doi: 10.1111/ajgw.12322
https://www.researchgate.net/publication/321754809

 

2016

Hirtz C, Vialaret J, Nowak N, Gabelle A, Deville de Périère D and Lehmann S.
Absolute quantification of 35 plasma biomarkers in human saliva using targeted mass spectrometry.
Bioanalysis (2016).
(IF :3.1) Jan;8(1):43-53. doi: 10.4155/bio.15.228
https://www.ncbi.nlm.nih.gov/pubmed/26647646

Hirtz C, Vialaret J, Gabelle A, Nowak N, Dauvilliers Y and Lehmann S.
From radioimmunoassay to mass spectrometry: a new method to quantify orexin-A (hypocretin-1) in cerebrospinal fluid.
Scientific Reports (2016). (IF:5.9) . 2016 May 11;6: 25162. doi: 10.1038/srep25162
https://www.ncbi.nlm.nih.gov/pubmed/27165941

Lehmann S, Vialaret J, Delatour V, Bros P, Brede C, Hirtz C and on behalf of the IFCC Working Group  on Clinical Quantitative Mass Spectrometry Proteomics (WG-cMSP).
Mass spectrometry proteomics for medical laboratory: what could be the future?
Clin Chem Lab Med (2016). (IF:3) pii: S0009-8981(16)30246-7. doi: 10.1016/j.cca.2016.06.001 
https://www.ncbi.nlm.nih.gov/pubmed/27265523

Hassan D, Provansal M, Lehmann S, Rizk M, Moez P, Vialaret J, Hirtz C, Essa A, Agamia H.
Proteomic profile of cerebrospinal fluid in patients with multiple sclerosis using two dimensional gel electrophoresis.
Br J Biomed Sci. (IF : 1.3)  2016 Jun 2:1-5. doi: 10.1080/09674845.2016.1186310
https://www.ncbi.nlm.nih.gov/pubmed/27254308

Renard D, Gabelle A, Hirtz C, Demattei C, Thouvenot E and Lehmann S.
Cerebrospinal fluid Alzheimer’s disease biomarkers in isolated supratentorial cortical superficial siderosis.
Journal of Alzheimer Disease (2016). (IF:4.1) 18;54(4):1291-1295. doi: 10.3233/JAD-160400
https://www.ncbi.nlm.nih.gov/pubmed/27567848

 

2015

Tall ML, Lehmann S, Diouf E, Gérard C,  Filali S, Hirtz C, Gabert L, Sauvinet V, Pirot F, Pivot C.
Injectable preparation of labeled leucine with the carbon 13 for a clinical research program on the Alzheimer disease: Pharmaceutical control of raw materials and the finished product and stability study.
Ann Pharm Fr (2015). 73(1):43-59. (IF : 0.58). doi: 10.1016/j.pharma.2014.06.002
https://www.ncbi.nlm.nih.gov/pubmed/25577016

Hirtz C, Lehmann S.
Blood sampling using « dried blood spot »: a clinical biology revolution underway?
Ann Biol Clin (Paris, 2015). Feb 1;73(1):25-37. (IF :1.9). doi: 10.1684/abc.2014.1007
https://www.ncbi.nlm.nih.gov/pubmed/25582720

Bros P, Vialaret J, Barthelemy N, Delatour V, Gabelle A, Lehmann S, Hirtz C.
Antibody-free quantification of seven tau peptides in human CSF using targeted mass spectrometry.
Front Neurosci (2015). 1;9: 302. (IF :3.7). doi: 10.3389/fnins.2015.00302
https://www.ncbi.nlm.nih.gov/pubmed/26388715

Morzel M, Neyraud E, Brignot H, Ducoroy P, Jeannin A, Lucchi G, Truntzer C, Canlet C, Tremblay-Franco M, Hirtz C, Gaillard S, Peretti N, Feron G.
Multi-omics profiling reveals that eating difficulties developed consecutively to artificial nutrition in the neonatal period are associated to specific saliva composition.
J Proteomics (2015). 128:105-12. (IF :3.9). doi: 10.1016/j.jprot.2015.07.028
https://www.ncbi.nlm.nih.gov/pubmed/26232109

Bros P, Delatour V, Vialaret J, Lalere B, Barthelemy N, Gabelle A, Lehmann S, Hirtz C.
Quantitative detection of amyloid-β peptides by mass spectrometry: state of the art and clinical applications.
Clin Chem Lab Med (2015). 1;53(10):1483-93. (IF : 3). doi: 10.1515/cclm-2014-1048
https://www.ncbi.nlm.nih.gov/pubmed/25719328

Lehmann S, Vialaret J, Gras Combe G, Bauchet L, Hanon O, Girard M, Gabelle A, Hirtz C.
Stable Isotope Labeling by Amino acid in Vivo (SILAV): a new method to explore protein metabolism.
Rapid Commun Mass Spectrom (2015). 30;29(20):1917-25. (IF:2.5). doi: 10.1002/rcm.7289  
https://www.ncbi.nlm.nih.gov/pubmed/26411513

Renard D, Waconge A, Ayrignac X, Mahmoud C, Fourcade G, Azakri S, Le Floch A, Bouly S, Marelli C, Tosi C, Arquizan C, Hirtz C, Gabelle A, Thouvenot E and Lehmann S.
Cerebropsinal fluid Alzheimer’s disease biomarkers in cerebral amyloid angiopathy-related inflammation.
Journal of Alzheimer Disease (2015). (IF:4.1) 50(3):759-64. doi: 10.3233/JAD-150621
https://www.ncbi.nlm.nih.gov/pubmed/26757185

Lehmann S, Hirtz C.
What is the potential of dried matrix spot sampling for cerebrospinal fluid analysis?
Bioanalysis (2015). (IF :3.1) Nov;7(22):2849-51. doi: 10.4155/bio.15.201
https://www.ncbi.nlm.nih.gov/pubmed/26600059

Bissonnette L, Antoine Y, Tiers L, Hirtz C, Lehmann S, Bissonnette F, Kadoch I.J, Haouzi D, Hamama S.
S100A10 plays a crucial role in the acquisition of the human endometrial receptivity phenotype and implantation process.
Journal of Cell Science (2015). (IF:4) Jan 13:0 3;10(3):282-98. doi: 10.1080/19336918.2015.1128623 
https://www.ncbi.nlm.nih.gov/pubmed/26760977

Barthélemy N, Fenaille F, Hirtz C, Sergeant N, Schraen-Maschke S, Vialaret J, Buée L, Gabelle A, Junot C, Lehmann S and Becher F.
Tau protein quantification in human cerebrospinal fluid by targeted mass spectrometry at high sequence coverage.
J.Prot (2015). Research. (IF: 5.46) 5;15(2):667-76. doi: 10.1021/acs.jproteome.5b01001
https://www.ncbi.nlm.nih.gov/pubmed/26742856

Hirtz C, Vialaret J, Nouadje G, Schraen S, Benlian P, Mary S, Philibert P, Tiers L, Bros P, Delaby C, Gabelle A, Lehmann S.
Comparison of LC-MRM Mass Spectrometry and semi-automatic Isofocusing approaches for the determination of Apolipoprotein E serotyping.
Clinica Chimica Acta (2015). (IF:3) 15;454:33-8. doi: 10.1016/j.cca.2015.12.020
https://www.ncbi.nlm.nih.gov/pubmed/26707914

 

2014
Delaby C, Gabelle A, Meynier P, Loubiere V, Vialaret J, Tiers L, Ducos J, Hirtz C and Lehmann S.
Development and validation of dried matrix spot sampling for the quantitative determination of amyloid beta peptides in cerebrospinal fluid.
Clin Chem Lab Med (2014). 23:1-7. (IF : 3) doi: 10.1515/cclm-2013-0611  
https://www.ncbi.nlm.nih.gov/pubmed/24150208
Lehmann S, Schraen S, Quadrio I, Paquet C, Bombois S, Delaby C, Dorey A, Dumurgier J, Hirtz C, Krolak-Salmon P, Laplanche JL, Moreaud O, Peoc’h K, Rouaud O, Sablonnière B, Thouvenot E, Touchon J, Vercruysse O, Hugon J, Gabelle A, Pasquier F, Perret-Liaudet A.
Impact of harmonization of collection tubes on Alzheimer’s disease diagnosis.
Alzheimers Dement (2014). S1552-5260(13)02495-3. (IF : 14.5). doi: 10.1016/j.jalz.2013.06.008
https://www.ncbi.nlm.nih.gov/pubmed/24269268

Delaby C, Vialaret J, Bros P, Gabelle A, Lefebvre T, Puy H, Hirtz C and Lehmann S.
Clinical measurement of Hepcidin-25 in human serum: Is quantitative mass spectrometry up to the job?
EuPA Open Proteomics (2014). Volume 3, Pages 60-67. (IF : 4.1). doi: 10.1016/j.euprot.2014.02.004 https://www.researchgate.net/publication/260367860

Lehmann S, Vialaret J, Seveno M, Tiers L, Gabelle A and  Hirtz C.
Comparison of hydrophobic, lipophilic and immunodepletion pre-fractionation methods for label-free LC-MS/MS identification of biomarkers in human cerebrospinal fluid.
Journal of Proteomics & Bioinformatics (2014). (IF : 2.6). doi: 10.4172/0974-276X.S5-003
http://dx.doi.org/10.4172/jpb.S5-003

Barthelemy N, Lehmann S, Hirtz C, Gabelle A, Sergeant N, Fenaille F, Vialaret J, Schraen S, Bros P, Tiers L, Delaby C, Junot C, Touchon J, Buee L, Becher F.
Detection and Quantification of the Tau Protein and Its Isoforms in the CSF of Alzheimer’s Disease Patients Using Mass Spectrometry.
Alzheimer’s & Dementia (2014). 10 (no. 4 sup): p. 147. (IF : 14.5). doi: 10.1016/j.jalz.2014.04.105
https://www.researchgate.net/publication/266895833  

 

2013

Lehmann S, Hoofnagle A, Hochstrasser D, Brede C, Glueckmann M, Cocho JA, Ceglarek U, Lenz C, Vialaret J, Scherl A, Hirtz C.
Quantitative Clinical Chemistry Proteomics (qCCP) using mass spectrometry: general characteristics and application.
Clin Chem Lab Med (2013). Nov 23:1-16. (IF : 3). doi: 10.1515/cclm-2012-0723
https://www.ncbi.nlm.nih.gov/pubmed/23183755

Lehmann S, Delaby C, Vialaret J, Ducos J, Hirtz C.
Current and future use of « dried blood spot » analyses in clinical chemistry.
Clin Chem Lab Med (2013). 1:1-13. (IF : 3). doi: 10.1515/cclm-2013-0228
https://www.researchgate.net/publication/237060490
Lehmann S, Delaby C, Touchon J, Hirtz C and Gabelle A.
Biomarkers of Alzheimer’s disease: the present and the future.
Rev. Neurol (2013). 1 6 9. 7 1 9 – 7 2 3. (IF : 0.6). doi: 10.1016/j.neurol.2013.07.012
https://www.ncbi.nlm.nih.gov/pubmed/24021316

 

2011

Lehmann S, Poinot P, Tiers L, Junot C, Becher F, Hirtz C.
From « Clinical Proteomics » to « Clinical Chemistry Proteomics »: considerations using quantitative mass-spectrometry as a model approach. 
Clin Chem Lab Med (2011). Oct 8;50(2):235-42. (IF : 3). doi: 10.1515/CCLM.2011.744
https://pubmed.ncbi.nlm.nih.gov/21981380/

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