The Blog

Yesterday, Stéphane successfully defended his thesis on the subject of the hybrid LBA-LCMS technique (capture by immuno-affinity combined with liquid chromatography-mass spectrometry) for the analysis and quantification of biomarkers and therapeutic or anti-drug...

Big news of the month; the arrival of the Alamar ARGO HT NULISA™ system, a major technological advance for the detection of previously inaccessible biomarkers. This technology enables the simultaneous analysis of up to 250 proteins, including critical biomarkers such...

This year's CSF Society conference was attended by a MIRIADE E.U. reunion in Barcelona! Charlotte Teunissen, Pablo Mohaupt and Anna Wojdała Wojdala gave an overview of the MIRIADE consortium structure, and the remarkable achievements since the project commencement....

Kick off meeting of the RHU secret gift : platelet repair system-based biotherapy of amyotrophic lateral sclerosis combining theragnostic biomarkers. This project aims to investigate blood and CSF biomarkers associated with amyotrophic lateral sclerosis. Dr. Jerome...

The PPC squat attended the American Society For Mass Spectrometry (ASMS) conference last week, and each of them presented a poster. Thank you to everyone who came to see us with interest and curiousity, it was great being there! Laura Fichter: Proteome and Tau...

Montpellier University Hospital launches ‘Les rendez-vous de la recherche’. To mark International Clinical Research Day, stands were set up at Montpellier University Hospital, and the PPC was also present! The aim was to showcase clinical research projects for the...

Association Des étoiles dans la mer, vaincre le glioblastome, an association dedicated to the fight against glioblastoma, interviewed Professor Christophe Hirtz on the crucial role of RNA in the diagnosis of glioblastoma. For more information, go check the interview:...

As is tradition, we're glad to welcome Belgian students from HOWEST University of Applied Sciences. This year, not one, but two students joined our team last month, Marit Van Assche and Ward Valcke, to do a 4-month internship for the end of their Licence 3. Marit will...

Our Jérôme Vialaret attended the 2024 Tau conference in Washington, where he presented a poster about the identification of Tau proteoforms in Alzheimer's Disease-derived EVs.

On March 12, we organized a Biocampus workshop with the PPM, discussing the present and future of clinical proteomics. This workshop included some interesting topics such as: - Deciphering the different proteomic analysis workflows, with their constraints and...

The PPC is in Lisbon !! Our Christophe Hirtz gave an oral presentation on friday : are synuclein's proteoforms good biomarkers of synucleinopathies (and how to quantify them)? Many thanks to Shimadzu Scientific Instruments for our fruitfull collaboration ! Also, our...

Last Friday, we were honored to welcome Dr. Koichi Tanaka (SHIMADZU- Koichi Tanaka Mass Spectrometry Research Laboratory), co-winner of the 2002 Nobel Prize in Chemistry, in our laboratory. It was an exciting occasion, with multiple presentations and interesting...

Deep phenotyping and new biomarkers for better patient stratification. The objective of the PPC is to set up biomarker’s innovative approaches for deep phenotyping associated with bioinformatics tools to integrate data analyses and store them within MESO@LR, the...

Last but not least, for 2023, Salomé Coppens defended her thesis topic, "Standardization of protein biomarkers: current status and future challenges, the case of Nf-L", with great skill and dedication. Congratulations Salomé on completing your doctoral degree, it's...

Since last week, Pablo Mohaupt can call himself a doctor after succesfully defending his PhD subject: “The Proteomic Landscape of Alzheimer's Disease”. Many congratulations on your impressive and rigorous work; you've proved yourself worthy of a doctorate. We look...

We celebrated Christmas early twice this year. First time with the our team, where we could finally take a new group picture! And a few days later, at our institute the IRMB. For the occasion, each team baked a cake related to their work. We've dedicated our cake to...

Our Sylvain Lehmann and Christophe Hirtz took part in a two-day meeting at the LNE site in Paris, to kick off the NEuroBioStand project! This project aims to standardize biomarker measurements for neurodegenerative diseases. Great discussions and exciting projects -...

ProFI is a national infrastructure in Proteomics and provide tools, methods and services to the academic and private partners in all fields of biology. The kick-off meeting of ProFI-Core, now replacing ProFI after its expansion, was held on 16th October 2023. The...

This week, a group of students from the Master 2 DMCC (Medical Devices from Design to Market) program came to visit our laboratory. Guided by Professor Hirtz, they were made aware of the crucial importance of biomarkers in a world where more and more people are faced...

The PPC team at American Society For Mass Spectrometry (ASMS) 2023, look at those happy faces! Jérôme Vialaret: Determination of a biomarkers panel to predict the response to treatment with dexamethasone for Sars-Cov2 / COVID-19 pneumonia Florine Leipp: Development of...

Last week, more than forty members of the Fondation pour la Recherche Médicale came to visit the laboratories of the Institute For Neurosciences Of Montpellier and the Institute for Regenerative Medicine & Biotherapy. Welcomed by Dr Sylvain Lehmann and his teams,...

Since Tuesday, Marie-Laure PONS can call herself a doctor after defending her PhD subject, development of an LC-MRM method for the quantification of synucleins in human builogical fluids in the context of neurodegenerative diseases. Many congratulations for the...

Many congratulations to doctor Amandine Amalric. Yesterday she defended her PhD subject, development of new cancer biomarkers based on RNA epigenetics, with great professionalism and confidence. We are all very proud of the work you have accomplished over the past...

The PPC team is very proud to announce that Jerome Vialaret has brilliantly defended his accreditation to supervise research (HDR) entitled: Biochemical diagnosis of neurodegenerative diseases: past, present and future. The HDR “recognises the candidate's high level...

After receiving our timsTOF HT as an early Christmas present in 2022, we finalized the setup by adding an ion bench for the EvosepOne. The coupling of an EvosepOne LC-system with the timsTOF HT mass spectrometer, is a perfect combination for high throughput mass...

Brain tumour: scientists from Montpellier develop a revolutionary diagnostic test Éric Rivals, a researcher at the LIRMM (Montpellier Laboratory of Informatics, Robotics and Microelectronics), Alexandre David, a biologist at the Institute of Functional Genomics, and...

Last week, two of our colleagues (Aurore Attina and Jana Kindermans Collinet) attended the Analytics2022 conference in Nantes, France. They met with our colleagues from the Montpellier proteome pole (PPM). Many thanks to the organizers for a wonderful and interesting...

This month, two students (Léa Barre and Maribelle Dossou-Yovo) from the Master 1 Biology-Health program followed us around the laboratory. We showed them how to work safely in a research lab and what it is like to do experiments. We hope they will be able to put this...

Last Friday, our intern Margaux Vignon presented a poster of a clinical study carried out within the Montpellier University Hospital at the European Congress of Periodontics and Implantology EuroPerio10 in Copenhagen. Poster title: Evaluation of post-operative...

We are happy to see our Technical Head, Jerome Vialaret, at the XIV Annual Congress of the European Proteomic Association in Leipzig. #EuPA2022

We continue our yearly tradition of bringing a Belgian student into our team. This year we are pleased to welcome Nikita De Wilde from HOWEST University of Applied Sciences (Hogeschool West-Vlaanderen), who will be doing a 4-month internship for the end of her Licence...

Let us introduce Margaux Vignon, another M2 BIOTIN student who will carry out her internship of six months in our laboratory. In a first phase, she will perform MSD immunoassays with Nelly Ginestet for the determination of protein biomarkers in patients with COVID 19....

This week we are happy to welcome another intern, Roumeissa Zouiher, a M2 BIOTIN student. She will stay six months to help our engineer Aurore Attina established a quality control for the analysis of RNA modifications by mass spectrometry. To do so, she will work in...

It's almost February, which means our interns are starting to arrive! This week we welcome our first intern of the year to arrive, Morgan Dornadic! She will be working by the side of our PhD student Marie-Laure Pons and will help her to develop a RT-QuIC (Real time...

Biomarkers for Alzheimer's disease, which can be measured by a simple blood test, will revolutionise the way Alzheimer's disease is diagnosed, making it simpler, quicker and less invasive. Today, lumbar puncture is often required to analyse cerebrospinal fluid.The...

The past two years have been a fruitful collaboration between our laboratory and the European Innovation Center from Shimadzu.A joint study for early detection of Alzheimer's disease biomarkers using mass spectrometry opens the door to new research advances. We...

This week, the M2 - DMCC students had the opportunity to visit our platform within the IRMB, accompanied by Professor Hirtz. We are always happy to show our platform to people interested in research!

Meet our team: a combination of engineers, technicians and PhD students. All our individual skills and knowledge combined makes our platform so much more interesting!

Latest news! Our new Simoa HD-X from Quanterix has arrived to replace our previous model HD-1. This model is a fully automated Simoa bead-based immunoassay platform and delivers major productivity improvements, greater user flexibility, unparalleled sensitivity, and...

Shimadzu: "Even during that pandemic situation, we continue to develop application, instrument solution for solving analytical problems with our partners accross Europe!" Our PlasmaBoost project (beta amyloid in blood) and the thesis of Marie-Laure PONS (synuclein...

Celebrate women's achievement. Raise awareness against bias. Take action for equality. #ChooseToChallenge With a special shoutout to the women in our team : Aurore ATTINA, Laura FICHTER, Nelly GINESTET, Jana KINDERMANS, Lisa MORICHON et Marie-Laure PONS. #IWD2021...

We are happy to announce a new project financed by the INCa in the framework of the Montpellier-based partnership* SMART: RNA methylation and FTO activity steer colorectal cancer cell phenotype Fat mass and Obesity-associated protein (FTO), a nuclear m6A demethylase,...

The PPC is happy to announce that we are strengthening our team with two new flemish students: Guillaume Le Berre and Ryan Trouvé. Both are students at HOWEST University of Applied Sciences (Hogeschool West-Vlaanderen) and are doing an internship during 4 months, at...

Axelle Vinot is doing an 8-week internship with us as part of her BTS with option in biotechnology. She will carry out assays on the Tau protein, an essential biomarker in the diagnosis of Alzheimer's disease, particularly in mass spectrometry.

Étienne Mondesert is a medical biology intern at the Montpellier University Hospital, doing a Master 2 internship at our platform. His work focuses on mass spectrometry quantification and clinical evaluation of a biomarker in the context of Parkinson disease.

Recently, our PhD student Marie-Laure PONS gave a presentation for her the thesis follow up committee. After one year of doing research and experimenting, her topic is beginning to take shape: the development of an innovative multiplex and targeted mass spectrometry...

Very proud of the financial support of @IsiteMUSE for our new CoVIMOD project dealing with an exhaustive analysis of the modification landscape of viral and cellular RNAs in SARS-CoV2 infection and the study of their functional impact on virus replication and cell...

Interested in using our numerous skills and techniques to analyse your samples? This workflow explains exactly how we work. For more information, check our website ppc-montpellier.com or contact us directly! #massspectrometry #proteomic #epitranscriptomics