{"id":1342,"date":"2021-02-24T12:10:16","date_gmt":"2021-02-24T11:10:16","guid":{"rendered":"https:\/\/ppc-montpellier.com\/?p=1342"},"modified":"2024-03-15T09:56:36","modified_gmt":"2024-03-15T08:56:36","slug":"a-new-project-financed-by-the-inca","status":"publish","type":"post","link":"https:\/\/ppc-montpellier.com\/index.php\/2021\/02\/24\/a-new-project-financed-by-the-inca\/","title":{"rendered":"A new project financed by the INCa"},"content":{"rendered":"\n<p>We are happy to announce a new project financed by the INCa in the framework of the Montpellier-based partnership* SMART: RNA methylation and FTO activity steer colorectal cancer cell phenotype<\/p>\n\n\n\n<p>Fat mass and Obesity-associated protein (FTO), a nuclear m6A demethylase, has been identified as the only m6A effector capable of bridging the CSC phenotype in colorectal cancer (S. Relier et al, Nature Communications 2021).<br> The aim is to characterize the molecular mechanisms connecting the dynamics of m6Am with the development of stem properties. As a result, it could lead to the identification of new targets, protein or RNA, to treat resistant forms of cancer.<\/p>\n\n\n\n<p>*Alexandre David (PI), Christophe Hirtz (IRMB\/PPC), E. Rivals (LIRMM) and Evelyne Crapez (ICM)<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>We are happy to announce a new project financed by the INCa in the framework of the Montpellier-based partnership* SMART: RNA methylation and FTO activity steer colorectal cancer cell phenotype Fat mass and Obesity-associated protein (FTO), a nuclear m6A demethylase, has been identified as the only m6A effector capable of bridging the CSC phenotype in [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":1340,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"categories":[22],"tags":[],"class_list":["post-1342","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-ppc-en"],"_links":{"self":[{"href":"https:\/\/ppc-montpellier.com\/index.php\/wp-json\/wp\/v2\/posts\/1342","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/ppc-montpellier.com\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/ppc-montpellier.com\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/ppc-montpellier.com\/index.php\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/ppc-montpellier.com\/index.php\/wp-json\/wp\/v2\/comments?post=1342"}],"version-history":[{"count":1,"href":"https:\/\/ppc-montpellier.com\/index.php\/wp-json\/wp\/v2\/posts\/1342\/revisions"}],"predecessor-version":[{"id":1343,"href":"https:\/\/ppc-montpellier.com\/index.php\/wp-json\/wp\/v2\/posts\/1342\/revisions\/1343"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/ppc-montpellier.com\/index.php\/wp-json\/wp\/v2\/media\/1340"}],"wp:attachment":[{"href":"https:\/\/ppc-montpellier.com\/index.php\/wp-json\/wp\/v2\/media?parent=1342"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/ppc-montpellier.com\/index.php\/wp-json\/wp\/v2\/categories?post=1342"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/ppc-montpellier.com\/index.php\/wp-json\/wp\/v2\/tags?post=1342"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}