[et_pb_section fb_built=”1″ fullwidth=”on” _builder_version=”4.16″ global_colors_info=”{}”][et_pb_fullwidth_header title=”Mass Spectrometry” subhead=”MRM or High Resolution, we have the solution to your problem” _builder_version=”4.16″ title_font=”Verdana|700|||||||” title_font_size=”48px” content_font=”Verdana||||||||” content_font_size=”16px” subhead_font=”Verdana||||||||” subhead_font_size=”16px” background_image=”https:\/\/ppc-montpellier.com\/wp-content\/uploads\/2019\/11\/PageSdeM.jpg” background_position=”bottom_center” global_colors_info=”{}”][\/et_pb_fullwidth_header][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”4.16″ custom_padding=”64px|0px|0|0px|false|false” global_colors_info=”{}”][et_pb_row _builder_version=”4.16″ custom_padding=”4px|0px|32px|0px|false|false” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.16″ text_font=”Verdana||||||||” text_font_size=”16px” global_colors_info=”{}”]<\/p>\n
To carry out its research and service activities, the PPC is equipped with the latest generation LC-MS\/MS mass spectrometry systems (Agilent Technologies, Bruker Daltonics and Shimadzu) as well as two biological sample preparation robots which represent an investment of 2.5 million Euros thanks to funds from the Occitania Region, mainly UM and CHU.<\/p>\n
[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”4.23.1″ use_background_color_gradient=”on” background_color_gradient_direction=”90deg” background_color_gradient_stops=”#f2f4fb 60%|rgba(255,255,255,0) 60%” background_color_gradient_start=”#f2f4fb” background_color_gradient_start_position=”60%” background_color_gradient_end=”rgba(255,255,255,0)” background_color_gradient_end_position=”60%” global_colors_info=”{}”][et_pb_row _builder_version=”4.23.1″ custom_padding=”32px|0px|66px|0px|false|false” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.27.4″ header_font=”||||||||” header_2_font=”Verdana||||||||” global_colors_info=”{}”]<\/p>\n
The \u00ab\u00a0Multiple Reaction Monitoring\u00bb\u00a0 (MRM) is an acquisition <\/span><\/span>method <\/span><\/span>highly specific, multiplex and sensitive<\/span><\/span>\u00a0for selectively <\/span><\/span>quantify analytes in complex matrix, and is widely used in the clinical setting for the targeted quantification of proteins or small molecules.<\/span><\/span><\/strong><\/span><\/p>\n \n [\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_2,1_2″ _builder_version=”4.16″ custom_padding=”32px|0px|66px|0px|false|false” global_colors_info=”{}”][et_pb_column type=”1_2″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.23.1″ text_font=”Verdana||||||||” text_font_size=”16px” global_colors_info=”{}”]<\/p>\n LCMS 8060NX<\/strong>\u00a0Shimadzu<\/em><\/p>\n The development of MRM methods can be carried out on different types of matrices, ranging from biological fluids (whole blood, urine) to cell culture, for example.<\/p>\n [\/et_pb_text][\/et_pb_column][et_pb_column type=”1_2″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/ppc-montpellier.com\/wp-content\/uploads\/2023\/12\/TQ-8060NX-Shimadzu-scaled.jpg” title_text=”TQ 8060NX Shimadzu” align_tablet=”center” align_phone=”center” align_last_edited=”on|desktop” _builder_version=”4.23.1″ global_colors_info=”{}”][\/et_pb_image][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”4.23.1″ custom_padding=”32px|0px|66px|0px|false|false” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.27.4″ header_font=”||||||||” header_2_font=”Verdana||||||||” custom_padding=”||0px|||” global_colors_info=”{}”]<\/p>\n \u00ab High Resolution Mass Spectrometry \u00bb\u00a0 (HRMS) allows the\u00a0<\/span><\/span>identification<\/span><\/span>\u00a0and <\/span><\/span>the\u00a0<\/span><\/span>characterization<\/span><\/span>\u00a0of thousands of proteins in complex mixtures.<\/span><\/span>\u200b [\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_2,1_2″ _builder_version=”4.16″ custom_padding=”50px|0px|66px|0px|false|false” global_colors_info=”{}”][et_pb_column type=”1_2″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/ppc-montpellier.com\/wp-content\/uploads\/2026\/08\/timsTOS_AIP.jpeg” title_text=”timsTOS_AIP” align_tablet=”center” align_phone=”center” align_last_edited=”on|desktop” _builder_version=”4.27.4″ global_colors_info=”{}”][\/et_pb_image][\/et_pb_column][et_pb_column type=”1_2″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.27.4″ text_font=”Verdana||||||||” text_font_size=”16px” hover_enabled=”0″ global_colors_info=”{}” sticky_enabled=”0″]<\/p>\n timsUltra AIP<\/strong>\u00a0Bruker + <\/em>proteoElute<\/strong> Bruker<\/em><\/p>\n The\u00a0timsTOF\u00a0Ultra AIP, combined with Bruker’s\u00a0ProteoElute\u00a0solution, is a next-generation proteomics platform designed for ultra-high-sensitivity analyses. Optimized to maximize performance from limited sample amounts, this system delivers deep proteomecoverage while ensuring outstanding robustness and reproducibility.\u200b<\/p>\n It is particularly well suited for\u00a0single-cell proteomics,\u00a0low-input proteomics, and\u00a0immunopeptidomics, enabling the analysisof rare samples, limited cell populations, and low-abundance peptides. This cutting-edge technology supports the mostdemanding projects in translational, biomedical, and fundamental proteomics research.\u200b<\/p>\n <\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_2,1_2″ _builder_version=”4.23.1″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”1_2″ _builder_version=”4.23.1″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.27.4″ text_font=”Verdana||||||||” text_font_size=”16px” custom_padding=”28px|||||” global_colors_info=”{}”]<\/p>\n timsTOF HT<\/strong>\u00a0Bruker + <\/em>Evosep One<\/strong> Evosep<\/em><\/p>\n The new timsTOF HT mass spectrometer is equipped with the 4th generation high capacity TIMS-XR analyzer and advanced digitizer technology (ADT). It offers higher dynamic range for unmatched analytical depth and quantitation in high-throughput proteomics experiments. The timsTOF HT is fully CCS-enabled and supports all PASEF<\/span>\u00a0acquisition modes including PASEF<\/span>, dia-PASEF<\/span>\u00a0and prm-PASEF<\/span>\u00a0achieving flexibility in 4D-Proteomics\u2122. Simply uncompromised proteomic depth at scale.<\/span> <\/span><\/p>\n The Evosep One is a standardized platform designed for robustness and high throughput. This is achieved by using Evotips as disposable trap columns, where samples are loaded and desalted offline. The autosampler picks up the tip and integrates elution with liquid chromatography. This removes sample handling steps and reduces injection cycle overheads.<\/span><\/span><\/p>\n [\/et_pb_text][\/et_pb_column][et_pb_column type=”1_2″ _builder_version=”4.23.1″ _module_preset=”default” global_colors_info=”{}”][et_pb_image src=”https:\/\/ppc-montpellier.com\/wp-content\/uploads\/2023\/12\/timsTOF-Bruker-scaled.jpg” title_text=”timsTOF Bruker” align_tablet=”center” align_phone=”center” align_last_edited=”on|desktop” _builder_version=”4.23.1″ global_colors_info=”{}”][\/et_pb_image][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”4.16″ use_background_color_gradient=”on” background_color_gradient_direction=”45deg” background_color_gradient_stops=”#182743 0%|#27364F 100%” background_color_gradient_start=”#182743″ background_color_gradient_end=”#27364F” custom_padding=”0|0px|64px|0px|false|false” global_colors_info=”{}”][et_pb_row column_structure=”1_2,1_4,1_4″ _builder_version=”4.16″ background_color=”#ffffff” global_colors_info=”{}”][et_pb_column type=”1_2″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/ppc-montpellier.com\/wp-content\/uploads\/2023\/12\/Team-2024.jpg” title_text=”Team 2024″ align_tablet=”center” align_phone=”center” align_last_edited=”on|desktop” _builder_version=”4.23.1″ max_width=”80%” module_alignment=”center” custom_padding=”|1px||30px” global_colors_info=”{}”][\/et_pb_image][\/et_pb_column][et_pb_column type=”1_4″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.16″ text_font=”Verdana||||||||” text_text_color=”#1E2D48″ header_font=”||||||||” header_text_color=”#1E2D48″ background_layout=”dark” global_colors_info=”{}”]<\/p>\n Institute for Regenerative Medicine & Biotherapy (IRMB)High Resolution Mass Spectrometry<\/strong><\/h2>\n
<\/span><\/span><\/span><\/strong><\/span><\/p>\nClinical Proteomics Platform<\/span><\/h3>\n
H\u00f4pital Saint Eloi
80 rue Augustin Fliche
34295 MONTPELLIER \u2013 Cedex 5
FRANCE<\/p>\n