{"id":981,"date":"2020-03-26T10:24:43","date_gmt":"2020-03-26T09:24:43","guid":{"rendered":"https:\/\/ppc-montpellier.com\/?page_id=981"},"modified":"2025-08-26T14:32:46","modified_gmt":"2025-08-26T12:32:46","slug":"spectrometrie-de-masse-en","status":"publish","type":"page","link":"https:\/\/ppc-montpellier.com\/index.php\/technologies-en\/spectrometrie-de-masse-en\/","title":{"rendered":"Spectrom\u00e9trie de masse — EN"},"content":{"rendered":"

[et_pb_section fb_built=”1″ fullwidth=”on” _builder_version=”4.16″ global_colors_info=”{}”][et_pb_fullwidth_header title=”Mass Spectrometry” subhead=”MRM or High Resolution, we have the solution to your problem” _builder_version=”4.16″ title_font=”Verdana|700|||||||” title_font_size=”48px” content_font=”Verdana||||||||” content_font_size=”16px” subhead_font=”Verdana||||||||” subhead_font_size=”16px” background_image=”https:\/\/ppc-montpellier.com\/wp-content\/uploads\/2019\/11\/PageSdeM.jpg” background_position=”bottom_center” global_colors_info=”{}”][\/et_pb_fullwidth_header][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”4.16″ custom_padding=”64px|0px|0|0px|false|false” global_colors_info=”{}”][et_pb_row _builder_version=”4.16″ custom_padding=”4px|0px|32px|0px|false|false” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.16″ text_font=”Verdana||||||||” text_font_size=”16px” global_colors_info=”{}”]<\/p>\n

To carry out its research and service activities, the PPC is equipped with the latest generation LC-MS\/MS mass spectrometry systems (Agilent Technologies, Bruker Daltonics and Shimadzu) as well as two biological sample preparation robots which represent an investment of 2.5 million Euros thanks to funds from the Occitania Region, mainly UM and CHU.<\/p>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”4.23.1″ use_background_color_gradient=”on” background_color_gradient_direction=”90deg” background_color_gradient_stops=”#f2f4fb 60%|rgba(255,255,255,0) 60%” background_color_gradient_start=”#f2f4fb” background_color_gradient_start_position=”60%” background_color_gradient_end=”rgba(255,255,255,0)” background_color_gradient_end_position=”60%” global_colors_info=”{}”][et_pb_row _builder_version=”4.23.1″ custom_padding=”32px|0px|66px|0px|false|false” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.23.1″ header_font=”||||||||” header_2_font=”Verdana||||||||” global_colors_info=”{}”]<\/p>\n

Multiple Reaction Monitoring<\/strong><\/h2>\n

Multiple Reaction Monitoring (MRM) is a MS technique widely used in the clinical setting for the targeted quantification of analytes or small molecules.<\/strong><\/span><\/p>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_2,1_2″ _builder_version=”4.16″ custom_padding=”32px|0px|66px|0px|false|false” global_colors_info=”{}”][et_pb_column type=”1_2″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.23.1″ text_font=”Verdana||||||||” text_font_size=”16px” global_colors_info=”{}”]<\/p>\n

LCMS 8060NX<\/strong>\u00a0Shimadzu<\/em><\/p>\n

The development of MRM methods can be carried out on different types of matrices, ranging from biological fluids (whole blood, urine) to cell culture, for example.<\/p>\n

[\/et_pb_text][\/et_pb_column][et_pb_column type=”1_2″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/ppc-montpellier.com\/wp-content\/uploads\/2023\/12\/TQ-8060NX-Shimadzu-scaled.jpg” title_text=”TQ 8060NX Shimadzu” align_tablet=”center” align_phone=”center” align_last_edited=”on|desktop” _builder_version=”4.23.1″ global_colors_info=”{}”][\/et_pb_image][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”4.23.1″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.23.1″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.23.1″ text_font=”Verdana|700|||||||” text_font_size=”17px” global_colors_info=”{}”]<\/p>\n

High<\/strong> Resolution Mass Spectrometry<\/strong><\/h2>\n

High-resolution mass spectrometry allows the identification and characterization of a large number of proteins in complex mixtures.<\/strong><\/p>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_2,1_2″ _builder_version=”4.16″ custom_padding=”50px|0px|66px|0px|false|false” global_colors_info=”{}”][et_pb_column type=”1_2″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/ppc-montpellier.com\/wp-content\/uploads\/2023\/12\/Q-TOF-Bruker-scaled.jpg” title_text=”Q-TOF Bruker” align_tablet=”center” align_phone=”center” align_last_edited=”on|desktop” _builder_version=”4.23.1″ global_colors_info=”{}”][\/et_pb_image][\/et_pb_column][et_pb_column type=”1_2″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.23.1″ text_font=”Verdana||||||||” text_font_size=”16px” global_colors_info=”{}”]<\/p>\n

Impact II<\/strong> Bruker + <\/em>nanoElute<\/strong> Bruker<\/em><\/p>\n

High performance proteomics and metabolomics studies using the impact II QTOF provide insight into how rational strain design increased bio-production efficiency. The Bruker impact II QTOF system is well suited to bottom-up proteomic and metabolomic workflows, and can be used to map the results of both metabolic and proteomic changes onto biochemical pathways.<\/span><\/p>\n

Bruker nanoElute is designed with years of proteomics know-how and nano-UHPLC expertise to deliver robust and reliable operation from the moment of installation through years of OMICS knowledge generation.\u00a0\u00a0<\/p>\n

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[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_2,1_2″ _builder_version=”4.23.1″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”1_2″ _builder_version=”4.23.1″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.23.1″ text_font=”Verdana||||||||” text_font_size=”16px” custom_padding=”28px|||||” global_colors_info=”{}”]<\/p>\n

TimsTOF HT<\/strong>\u00a0Bruker + <\/em>Evosep One<\/strong> Evosep<\/em><\/p>\n

The new timsTOF HT mass spectrometer is equipped with the 4th generation high capacity TIMS-XR analyzer and advanced digitizer technology (ADT). It offers higher dynamic range for unmatched analytical depth and quantitation in high-throughput proteomics experiments. The timsTOF HT is fully CCS-enabled and supports all PASEF<\/span>\u00a0acquisition modes including PASEF<\/span>, dia-PASEF<\/span>\u00a0and prm-PASEF<\/span>\u00a0achieving flexibility in 4D-Proteomics\u2122. Simply uncompromised proteomic depth at scale.<\/span> <\/span><\/p>\n

The Evosep One is a standardized platform designed for robustness and high throughput. This is achieved by using Evotips as disposable trap columns, where samples are loaded and desalted offline. The autosampler picks up the tip and integrates elution with liquid chromatography. This removes sample handling steps and reduces injection cycle overheads.<\/span><\/span><\/p>\n

[\/et_pb_text][\/et_pb_column][et_pb_column type=”1_2″ _builder_version=”4.23.1″ _module_preset=”default” global_colors_info=”{}”][et_pb_image src=”https:\/\/ppc-montpellier.com\/wp-content\/uploads\/2023\/12\/timsTOF-Bruker-scaled.jpg” title_text=”timsTOF Bruker” align_tablet=”center” align_phone=”center” align_last_edited=”on|desktop” _builder_version=”4.23.1″ global_colors_info=”{}”][\/et_pb_image][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”4.23.1″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.23.1″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.27.4″ text_font=”Verdana|700|||||||” text_font_size=”17px” hover_enabled=”0″ global_colors_info=”{}” sticky_enabled=”0″]<\/p>\n

High Performance Mass Detection<\/strong><\/h2>\n

\u00a0By a Matrix-Assisted Laser Desorption\/Ionization Time-of-Flight Mass Spectrometer.<\/span><\/p>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_2,1_2″ _builder_version=”4.16″ custom_padding=”24px|0px|66px|0px|false|false” global_colors_info=”{}”][et_pb_column type=”1_2″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/ppc-montpellier.com\/wp-content\/uploads\/2023\/12\/MALDI-TOF-Shimadzu-scaled.jpg” title_text=”MALDI-TOF Shimadzu” align_tablet=”center” align_phone=”center” align_last_edited=”on|desktop” _builder_version=”4.23.1″ global_colors_info=”{}”][\/et_pb_image][\/et_pb_column][et_pb_column type=”1_2″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.16″ text_font=”Verdana||||||||” text_font_size=”16px” global_colors_info=”{}”]<\/p>\n

Axima Assurance<\/strong> Shimadzu<\/em><\/p>\n

<\/em><\/p>\n